Tabex Tablets Reviews
For the people who have asked here are two curated ‘Tabex Tablets Reviews’.
Tabex is also known as ‘Cytisine’, an anti-smoking drug more widely used in Eastern European countries.
It has been in use for over 40 years. Here is a clip from Wikipedia…
In 2011, a randomized controlled trial with 740 patients found cytisine improved 12-month abstinence from nicotine from 2.4% with placebo to 8.4% with cytisine. A 2013 meta-analysis of eight studies demonstrated that cytisine has similar effectiveness to varenicline which is already licensed in the US but with substantially lower side effects. A 2014 systematic review and economic evaluation concluded that cytisine was more likely to be cost-effective for smoking cessation than varenicline.
I have another snippet of information on Tabex tablets from the NIH.gov
As well as producing promising results, the drug is reported to be inexpensive, which singles it out as a potential future treatment within the UK. However, given that the trial was relatively small and short it is likely that more research will be needed to confirm its effectiveness and safety before regulators can approve its use.
The organisation that oversees drug licensing in the UK, the Medicines and Healthcare products Regulatory Agency (MHRA), says it has not received an application to license Tabex. The MHRA says: “Whilst we welcome new applications for promising medicines for use in the UK, it’s imperative that the product’s safety, quality and effectiveness is assessed to ensure the benefits outweigh the risks. It would be wrong to assume that the product has no known harmful side effect. All medicines have side effects – no effective medicine is without any risk.”
If you are wondering about the results achieved here is another piece of info from the NHK…
Results after 12 months showed that 8.4% of the participants randomised to receive cytisine had not relapsed (in other words, had successfully quit smoking), compared to 2.4% of the participants randomised to receive placebo. This was a difference of 6% (95% CI 2.7% to 9.2%), which equated to people taking cytisine being 3.4 times more likely to give up than those taking a placebo (95% CI 1.7 to 7.1).
What are the most common side effects?
Gastrointestinal (stomach and intestine) side effects, predominantly stomach-ache, dry mouth, dyspepsia and nausea, were reported significantly more frequently in participants receiving cytisine (13.8%) than those receiving placebo (8.1%). There were no other side effects, which were significantly more frequent in the group receiving cytisine. The two groups had similar rates of drug discontinuation and dose reduction.
Is the Tabex considered safe?
Although this study only lasted 12 months and was not large enough for an assessment of uncommon adverse events, the researchers report that the latest Periodic Safety Update Report provided to the European Authorities, based on more than 7 million exposed persons, did not identify any safety signals: in other words, the drug is considered safe.
Conclusion:
I’m afraid I don’t have a one-size-fits-all conclusion, so check the links to the relevant articles so you can draw your own conclusions.
See our home page ‘Nicotine Slave‘ for further articles and information.
